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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sadler, Carl | RP | Atlanta Braves | 32 | 10/11/1976 | Gainesville | USA | Left | Left | 6' 2" | 185 lbs | $1,140,000 |
| Salas, Fernando | RP | Los Angeles Dodgers | 24 | 05/30/1985 | Huatabampo | MEX | Right | Right | 6' 2" | 200 lbs | $2,480,000 |
| Salazar, Oscar | LF | San Francisco Giants | 31 | 06/27/1978 | Maracay | VEN | Right | Right | 5' 11" | 180 lbs | $9,900,000 |
| Samardzija, Jeff | SP | Montreal Expos | 24 | 01/23/1985 | Merrillville | USA | Right | Right | 6' 5" | 215 lbs | $2,000,000 |
| Sanchez, Freddy | 2B | San Francisco Giants | 31 | 12/21/1977 | Hollywood | USA | Right | Right | 5' 11" | 190 lbs | $1,600,000 |
| Sanders, Clifford | LF | Boston Red Sox | 28 | 06/29/1981 | White Oak East | USA | Left | Left | 5' 9" | 165 lbs | $6,660,000 |
| Sandoval, Pablo | 3B | Arizona Diamondbacks | 22 | 08/11/1986 | Puerto Cabello | VEN | Switch | Right | 5' 11" | 240 lbs | $158,400 |
| Santana, Johan | SP | Toronto Blue Jays | 30 | 03/13/1979 | Unknown | VEN | Left | Left | 6' 0" | 200 lbs | $15,200,000 |
| Santos, Carlos | RP | Texas Rangers | 30 | 11/25/1978 | Cedar Rapids | USA | Right | Right | 6' 0" | 205 lbs | $4,200,000 |
| Saslove, Camden | SP | Philadelphia Phillies | 28 | 03/23/1981 | Toronto | CAN | Right | Left | 6' 6" | 200 lbs | $158,400 |
| Scheppers, Tanner | RP | Free Agent | 22 | 01/17/1987 | Mission Viejo | USA | Right | Right | 6' 4" | 220 lbs | - |
| Schied, Hackett | RP | Toronto Blue Jays | 30 | 03/27/1979 | Mobile | USA | Left | Left | 5' 11" | 200 lbs | $620,950 |
| Schmidt, Bryan | SP | San Francisco Giants | 26 | 07/20/1982 | New York | USA | Switch | Right | 6' 2" | 200 lbs | $158,400 |
| Schmidt, Jason | SP | Montreal Expos | 36 | 01/29/1973 | Lewiston | USA | Right | Right | 6' 5" | 195 lbs | $1,400,000 |
| Schroeder, Bob | 2B | Seattle Mariners | 28 | 04/12/1981 | Dallas | USA | Right | Right | 6' 1" | 195 lbs | $441,200 |
| Schultz, Jack | 1B | Houston Astros | 28 | 06/01/1981 | Jacksonville | USA | Left | Left | 6' 6" | 220 lbs | $158,400 |
| Scott, António | 2B | Free Agent | 29 | 10/06/1979 | Manchester | USA | Right | Right | 6' 0" | 185 lbs | - |
| Scott, Luke | LF | Chicago Cubs | 31 | 06/25/1978 | Unknown | USA | Left | Right | 6' 0" | 205 lbs | $370,000 |
| Seay, Bobby | RP | Colorado Rockies | 31 | 06/20/1978 | Sarasota | USA | Left | Left | 6' 2" | 220 lbs | $8,500,000 |
| Sellek, Bob | SP | Free Agent | 26 | 09/19/1982 | Euclid | USA | Right | Right | 6' 4" | 205 lbs | - |
| Shackelford, Kevin | RP | Free Agent | 20 | 04/07/1989 | Charlotte | USA | Right | Right | 6' 5" | 215 lbs | - |
| Sheets, Ben | SP | Baltimore Orioles | 30 | 07/18/1978 | Baton Rouge | USA | Right | Right | 6' 1" | 190 lbs | $2,600,000 |
| Shelton, Chris | 1B | Free Agent | 29 | 06/26/1980 | Salt Lake City | USA | Right | Right | 6' 0" | 215 lbs | - |
| Shelton, Dan | LF | Montreal Expos | 33 | 12/05/1975 | Mack South | USA | Left | Left | 6' 4" | 195 lbs | $9,400,000 |
| Shelton, Jim | RP | Free Agent | 25 | 09/17/1983 | Tallahassee | USA | Right | Right | 6' 1" | 195 lbs | - |
| Shields, James | SP | San Diego Padres | 26 | 12/20/1982 | Newhall | USA | Right | Right | 6' 4" | 215 lbs | $8,200,000 |
| Shoemaker, Matt | SP | Baltimore Orioles | 22 | 09/27/1986 | Wyandotte | USA | Right | Right | 6' 2" | 220 lbs | $158,400 |
| Simpson, Edmond | 2B | Free Agent | 31 | 02/18/1978 | Dover | USA | Right | Right | 6' 2" | 205 lbs | - |
| Skinner, Brad | 1B | Chicago Cubs | 27 | 10/16/1981 | Molalla | USA | Left | Left | 6' 4" | 210 lbs | $158,400 |
| Slowey, Kevin | RP | Chicago Cubs | 25 | 05/04/1984 | Conroe | USA | Right | Right | 6' 3" | 200 lbs | $158,400 |
| Small, Errol | RP | New York Yankees | 27 | 11/10/1981 | Cherry Hill | USA | Left | Right | 6' 4" | 200 lbs | $158,400 |
| Smith, Matt | 2B | San Diego Padres | 30 | 01/21/1979 | Caldwell | USA | Left | Right | 6' 3" | 200 lbs | $2,320,000 |
| Smith, Tom | CF | Texas Rangers | 27 | 07/24/1981 | Pioneer Village | USA | Right | Right | 6' 1" | 190 lbs | $158,400 |
| Snell, Ian | RP | Los Angeles Dodgers | 26 | 10/30/1982 | Dover | USA | Right | Right | 5' 11" | 175 lbs | $490,000 |
| Snelling, Chris | LF | San Francisco Giants | 26 | 12/03/1982 | North Miami | USA | Left | Left | 5' 10" | 175 lbs | $545,100 |
| Soria, Joakim | CL | Boston Red Sox | 25 | 05/18/1984 | Monclova | MEX | Right | Right | 6' 2" | 180 lbs | $547,425 |
| Soto, Geovany | C | San Diego Padres | 26 | 01/20/1983 | San Juan | PUR | Right | Right | 6' 1" | 225 lbs | $368,000 |
| Span, Denard | RF | Montreal Expos | 25 | 02/27/1984 | Tampa | USA | Left | Left | 6' 0" | 210 lbs | $158,400 |
| Spivey, Junior | 2B | Free Agent | 34 | 01/28/1975 | Oklahoma City | USA | Right | Right | 6' 0" | 200 lbs | - |
| St.george, Kinnon | LF | Los Angeles Dodgers | 25 | 12/06/1983 | Calgary | CAN | Left | Left | 5' 10" | 185 lbs | $158,400 |
| Strasburg, Stephen | SP | Baltimore Orioles | 20 | 07/20/1988 | San Diego | USA | Right | Right | 6' 4" | 215 lbs | $158,400 |
| Street, Huston | CL | Montreal Expos | 25 | 08/02/1983 | Austin | USA | Right | Right | 6' 0" | 180 lbs | $158,400 |
| Stubbs, Drew | CF | Toronto Blue Jays | 24 | 10/04/1984 | Texarkana | USA | Right | Right | 6' 4" | 200 lbs | $1,700,000 |
| Suzuki, Kurt | C | Toronto Blue Jays | 25 | 10/04/1983 | Wailuku | USA | Right | Right | 6' 0" | 205 lbs | $1,200,000 |
| Sweeney, Ryan | CF | Toronto Blue Jays | 24 | 02/20/1985 | Cedar Rapids | USA | Left | Left | 6' 4" | 200 lbs | $158,400 |
| Sánchez, Armando | SS | Chicago Cubs | 31 | 09/20/1977 | Bellevue | USA | Right | Right | 6' 2" | 200 lbs | $680,000 |
