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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Player | From-To | W | L | Pct | ERA | G | GS | CG | SHO | SV | IP | H | ER | HR | BB | SO |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Blake O'Brien | 2045-2048 | 4 | 4 | .500 | 6.13 | 28 | 12 | 0 | 0 | 0 | 86.2 | 95 | 59 | 20 | 68 | 106 |
| Tristan O'Neal | 2048-2051 | 11 | 12 | .478 | 3.58 | 40 | 40 | 0 | 0 | 0 | 193.2 | 172 | 77 | 9 | 91 | 240 |
| Glen O'Reilly | 1990-1993 | 8 | 5 | .615 | 2.75 | 85 | 0 | 0 | 0 | 41 | 98.1 | 70 | 30 | 9 | 42 | 164 |
| Ian Oberle | 2016-2017 | 10 | 4 | .714 | 4.12 | 22 | 22 | 0 | 0 | 0 | 111.1 | 84 | 51 | 12 | 50 | 99 |
| T.J. Oberstar | 2015-2016 | 2 | 3 | .400 | 8.82 | 44 | 0 | 0 | 0 | 0 | 50.0 | 64 | 49 | 12 | 39 | 53 |
| Tamasaburo Okamoto | 1988-1988 | 4 | 1 | .800 | 1.86 | 10 | 10 | 0 | 0 | 0 | 67.2 | 58 | 14 | 7 | 8 | 72 |
| Tatsuya Okinaka | 2026-2027 | 4 | 5 | .444 | 3.85 | 22 | 22 | 0 | 0 | 0 | 110.0 | 118 | 47 | 14 | 39 | 119 |
| Fernando Olivares | 1999-2002 | 23 | 11 | .676 | 3.03 | 42 | 42 | 0 | 0 | 0 | 279.0 | 229 | 94 | 31 | 55 | 334 |
| Willie Olivas | 2017-2018 | 6 | 2 | .750 | 2.69 | 22 | 22 | 1 | 1 | 0 | 110.1 | 88 | 33 | 10 | 41 | 133 |
| Pat Olson | 1997-2000 | 25 | 12 | .676 | 3.34 | 43 | 43 | 3 | 0 | 0 | 285.1 | 251 | 106 | 15 | 70 | 333 |
| Ogden Orozco | 2036-2037 | 3 | 3 | .500 | 13.83 | 53 | 1 | 0 | 0 | 0 | 54.2 | 73 | 84 | 17 | 88 | 49 |
| Zach Orr | 2036-2037 | 6 | 3 | .667 | 10.74 | 39 | 1 | 0 | 0 | 1 | 58.2 | 71 | 70 | 13 | 74 | 58 |
| J.J. Ortega | 2050-2053 | 11 | 4 | .733 | 4.40 | 52 | 5 | 0 | 0 | 10 | 90.0 | 64 | 44 | 14 | 50 | 156 |
| Alex Ortigoza | 2003-2005 | 8 | 10 | .444 | 3.66 | 22 | 22 | 0 | 0 | 0 | 125.1 | 132 | 51 | 10 | 46 | 142 |
| DeJohn Ortiz | 2059-2060 | 3 | 4 | .429 | 4.50 | 20 | 20 | 0 | 0 | 0 | 98.0 | 96 | 49 | 21 | 35 | 107 |
| Clarence OrtÃz | 1988-1988 | 5 | 0 | 1.000 | 1.57 | 14 | 14 | 0 | 0 | 0 | 86.0 | 67 | 15 | 2 | 13 | 137 |
| Dave Osborn | 2031-2032 | 3 | 6 | .333 | 4.29 | 21 | 21 | 0 | 0 | 0 | 105.0 | 99 | 50 | 16 | 36 | 106 |
| Jarrett Osborne | 2047-2047 | 3 | 0 | 1.000 | 4.00 | 13 | 0 | 0 | 0 | 0 | 27.0 | 29 | 12 | 5 | 16 | 30 |
| Logan Osborne | 2051-2053 | 2 | 3 | .400 | 6.46 | 37 | 0 | 0 | 0 | 1 | 54.1 | 41 | 39 | 13 | 47 | 72 |
| Harvey Owens | 2051-2053 | 3 | 4 | .429 | 4.12 | 31 | 16 | 0 | 0 | 8 | 96.0 | 98 | 44 | 10 | 36 | 98 |
